Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More

53BP1 Rabbit anti-Human, Mouse, Biotin, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA522790

Catalog No. PIPA522790


Add to cart

Description

Description

This antibody reacts with Human samples in Western blot and ICC applications, and with Mouse in ICC applications.

53BP1 (P53-binding protein 1) plays a critical role in tumor suppression and is a putative substrate of ATM kinase. Upon DNA damage, 53BP1 is phosphorylated and localizes to the presumptive sites of damage, specifically, double-strand breaks. 53BP1 may have a role in checkpoint signaling during mitosis, enhances TP53-mediated transcriptional activation, and participates in DNA repair by maintaining genomic stability.
Specifications

Specifications

53BP1
Polyclonal
Biotin
TP53BP1
Liquid
TP53BP1, Trp53bp1
A synthetic peptide, which represented a portion of human tumor protein p53-binding protein 1 encoded in exon 11, 12 and 19 (LocusLink ID 7158). This antibody is a cocktail hybrid of NB 100-304 and NB 100-305.
Antigen affinity chromatography
RUO
Antibody
Polyclonal
Human, Mouse
Immunocytochemistry, Immunofluorescence, Western Blot
1 mg/mL
PBS with no preservative
Q12888, P70399
53BP1, p202, p53-binding protein 1, p53BP1, tumor protein 53-binding protein, 1, tumor protein p53-binding protein, 1, tumor suppressor p53-binding protein 1
Rabbit
IgG
100 μL
4° C, store in dark
Primary
27223, 7158
Documents
Provide Content Correction

We continue to work to improve your shopping experience and your feedback regarding this content is very important to us. Please use the form below to provide feedback related to the content on this product.

Product Title

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.

Cancel Submit