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53BP1 Rabbit anti-Human, Mouse, DyLight® 550, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA522794

Catalog No. PIPA522794

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This antibody reacts with Human samples in Western blot and ICC applications, and with Mouse in ICC applications.

53BP1 (P53-binding protein 1) plays a critical role in tumor suppression and is a putative substrate of ATM kinase. Upon DNA damage, 53BP1 is phosphorylated and localizes to the presumptive sites of damage, specifically, double-strand breaks. 53BP1 may have a role in checkpoint signaling during mitosis, enhances TP53-mediated transcriptional activation, and participates in DNA repair by maintaining genomic stability.


DyLight™ 550
TP53BP1, Trp53bp1
A synthetic peptide, which represented a portion of human tumor protein p53-binding protein 1 encoded in exon 11, 12 and 19 (LocusLink ID 7158). This antibody is a cocktail hybrid of NB 100-304 and NB 100-305.
Antigen affinity chromatography
Human, Mouse
Immunocytochemistry, Immunofluorescence, Western Blot
0.87 mg/mL
50mM sodium borate with 0.05% sodium azide
Q12888, P70399
53BP1, p202, p53-binding protein 1, p53BP1, tumor protein 53-binding protein, 1, tumor protein p53-binding protein, 1, tumor suppressor p53-binding protein 1
100 μL
4° C, store in dark
27223, 7158
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