AAK1 Rabbit anti-Human, Polyclonal, Invitrogen
Rabbit Polyclonal Antibody
Manufacturer: Invitrogen PA515023
This antibody is predicted to react with bovine, mouse, porcine and rat based on sequence homology.Adaptor-related protein complex 2 (AP-2 complexes) functions during receptor-mediated endocytosis to trigger clathrin assembly, interact with membrane-bound receptors, and recruit encodytic accessory factors. AAK1 is a member of the SNF1 subfamily of Ser/Thr protein kinases. The protein interacts with and phosphorylates a subunit of the AP-2 complex, which promotes binding of AP-2 to sorting signals found in membrane-bound receptors and subsequent receptor endocytosis. Its kinase activity is stimulated by clathrin.
|PBS with 0.09% sodium azide|
|AP2-associated protein kinase 1; Adaptor-associated kinase 1; AAK1; KIAA1048|
|-20° C, Avoid Freeze/Thaw Cycles|
|KLH conjugated synthetic peptide between 790-819 amino acids from the C-terminal region of human AAK1|
|Ammonium sulfate precipitation, Size-exclusion - Dialysis|
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