AANAT Rabbit anti-Human, Polyclonal, Invitrogen
Rabbit Polyclonal Antibody
Manufacturer: Invitrogen PA526631
PA5-26631 has successfully been used to detect serotonin N-AT in both WB and IF applications.AANAT belongs to the acetyltransferase superfamily. It is the penultimate enzyme in melatonin synthesis and controls the night/day rhythm in melatonin production in the vertebrate pineal gland. Melatonin is essential for the function of the circadian clock that influences activity and sleep. This enzyme is regulated by cAMP-dependent phosphorylation that promotes its interaction with 14-3-3 proteins and thus protects the enzyme against proteasomal degradation. This gene may contribute to numerous genetic diseases such as delayed sleep phase syndrome.
|PBS with 0.09% sodium azide|
|DSPS, SNAT, arylalkylamine N-acetyltransferase, serotonin N-acetyltransferase, serotonin acetylase|
|-20° C, Avoid Freeze/Thaw Cycles|
|Immunofluorescence, Western Blot|
|KLH conjugated synthetic peptide between 27-54 amino acids from the N-terminal region of human AANAT|
|Antigen Affinity Chromatography, Protein A|
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