Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More

ABAT Rabbit anti-Human, Mouse, Rat, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA527198

Catalog No. PIPA527198


Add to cart

Description

Description

PA5-27198 targets ABAT in Immunofluorescence, Western blot, and immunohistochemistry (paraffin) applications and shows reactivity with Human, rat, and mouse samples. The PA5-27198 immunogen is recombit fragment corresponding to a region within amino acids 1 and 245 of Human ABAT. Store product as a concentrated solution. Centrifuge briefly prior to opening the vial. For short-term storage (1-2 weeks), product can be stored at 4°C. For long-term storage, aliquot and store product at -20° C or below, avioiding multiple freeze-thaw cycles.

4-aminobutyrate aminotransferase (ABAT) is responsible for catabolism of gamma-aminobutyric acid (GABA), an important, mostly inhibitory neurotransmitter in the central nervous system, into succinic semialdehyde. The active enzyme is a homodimer of 50-kD subunits complexed to pyridoxal-5-phosphate. The protein sequence is over 95% similar to the pig protein. GABA is estimated to be present in nearly one-third of human synapses. ABAT in liver and brain is controlled by 2 codomit alleles with a frequency in a Caucasian population of 0.56 and 0.44. The ABAT deficiency phenotype includes psychomotor retardation, hypotonia, hyperreflexia, lethargy, refractory seizures, and EEG abnormalities. Multiple alternatively spliced transcript variants encoding the same protein isoform have been found for this gene.
Specifications

Specifications

ABAT
Polyclonal
Unconjugated
ABAT
Liquid
ABAT
Recombit fragment corresponding to a region within amino acids 1 and 245 of Human ABAT
Antigen affinity chromatography
RUO
Antibody
Polyclonal
Human, Mouse, Rat
Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
1 mg/mL
PBS with 20% glycerol and 0.01% thimerosal; pH 7
P80404, P61922, P50554
GABA-AT, GABAT, NPD009, (S)-3-amino-2-methylpropionate transaminase, 4-aminobutyrate aminotransferase, mitochondrial, 4-aminobutyrate transaminase, GABA aminotransferase, GABA transaminase, GABA transferase, gamma-amino-N-butyrate transaminase
Rabbit
IgG
100 μL
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Primary
18, 268860, 81632
Documents
Provide Content Correction

We continue to work to improve your shopping experience and your feedback regarding this content is very important to us. Please use the form below to provide feedback related to the content on this product.

Product Title

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.

Cancel Submit