Abl2 Rabbit anti-Human, Polyclonal, Invitrogen
Rabbit Polyclonal Antibody
Manufacturer: Invitrogen PA527926
PA5-27926 targets ABL2 in WB applications and shows reactivity with Human samples. The PA5-27926 immunogen is recombit fragment corresponding to a region within amino acids 55 and 470 of Human ABL2. Store product as a concentrated solution. Centrifuge briefly prior to opening the vial. For short-term storage (1-2 weeks), product can be stored at 4°C. For long-term storage, aliquot and store product at -20° C or below, avioiding multiple freeze-thaw cycles.This gene encodes a member of the Abelson family of nonreceptor tyrosine protein kinase. The protein is highly similar to the ABL1 protein, including the tyrosine kinase, SH2 and SH3 domains, and has a role in cytoskeletal rearrangements by its C-terminal F-actin- and microtubule-binding sequences. This gene is expressed in both normal and tumor cells, and is involved in translocation with the ETV6 gene in leukemia. Multiple alternatively spliced transcript variants encoding different protein isoforms have been found for this gene.
|Recombit fragment corresponding to a region within amino acids 55 and 470 of Human ABL2|
|Antigen affinity chromatography|
|0.1M tris glycine with 20% glycerol and 0.01% thimerosal; pH 7|
|ABLL, ARG, Abelson tyrosine-protein kinase 2, abelson-related gene protein, tyrosine-protein kinase ARG|
|Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
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