ACK1 Rabbit anti-Human, Polyclonal, Invitrogen
Rabbit Polyclonal Antibody
Manufacturer: Invitrogen PA514764
This antibody is predicted to react with bovine based on sequence homology.ACK1 is a tyrosine kinase that binds Cdc42Hs in its GTP-bound form and inhibits both the intrinsic and GTPase-activating protein (GAP)-stimulated GTPase activity of Cdc42Hs. This binding is mediated by a unique sequence of 47 amino acids C-terminal to an SH3 domain. The protein may be involved in a regulatory mechanism that sustains the GTP-bound active form of Cdc42Hs and which is directly linked to a tyrosine phosphorylation signal transduction pathway.
|PBS with 0.09% sodium azide|
|Activated p21cdc42Hs kinase|
|-20° C, Avoid Freeze/Thaw Cycles|
|Flow Cytometry, Immunohistochemistry, Western Blot|
|KLH conjugated synthetic peptide between 10-39 amino acids from the N-terminal region of human ACK1|
|Ammonium sulfate precipitation, Size-exclusion - Dialysis|
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