ACVR1C Rabbit anti-Human, Polyclonal, Invitrogen
Rabbit Polyclonal Antibody
Manufacturer: Invitrogen PA527904
PA5-27904 targets Activin A Receptor Type IC in IHC (P) and WB applications and shows reactivity with Human samples. The PA5-27904 immunogen is recombit fragment corresponding to a region within amino acids 19 and 426 of Human Activin A Receptor Type IC. Store product as a concentrated solution. Centrifuge briefly prior to opening the vial. For short-term storage (1-2 weeks), product can be stored at 4°C. For long-term storage, aliquot and store product at -20° C or below, avioiding multiple freeze-thaw cycles.ACVR1C is a type I receptor for the TGFB (see MIM 190180) family of signaling molecules. Upon ligand binding, type I receptors phosphorylate cytoplasmic SMAD transcription factors, which then translocate to the nucleus and interact directly with DNA or in complex with other transcription factors (Bondestam et al., 2001 [PubMed 12063393]).
|Recombit fragment corresponding to a region within amino acids 19 and 426 of Human Activin A Receptor Type IC|
|Antigen affinity chromatography|
|Immunohistochemistry (Paraffin), Western Blot|
|PBS with 1% BSA, 20% glycerol and 0.01% thimerosal; pH 7|
|ACVRLK7, ALK7, ACTR-IC, ALK-7, activin receptor type IC, activin receptor type-1C, activin receptor-like kinase 7|
|Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
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