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ACVRL1 Rabbit anti-Human, Mouse, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA527081

Catalog No. PIPA527081


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Description

Description

PA5-27081 targets Activin A Receptor Type II-like 1 in IHC (P) and WB applications and shows reactivity with Human and mouse samples. The PA5-27081 immunogen is synthetic peptide corresponding to a region within amino acids 441 and 503 of Human Activin A Receptor Type II-like 1. Store product as a concentrated solution. Centrifuge briefly prior to opening the vial. For short-term storage (1-2 weeks), product can be stored at 4°C. For long-term storage, aliquot and store product at -20° C or below, avioiding multiple freeze-thaw cycles.

This gene encodes a type I cell-surface receptor for the TGF-beta superfamily of ligands. It shares with other type I receptors a high degree of similarity in serine-threonine kinase subdomains, a glycine- and serine-rich region (called the GS domain) preceding the kinase domain, and a short C-terminal tail. The encoded protein, sometimes termed ALK1, shares similar domain structures with other closely related ALK or activin receptor-like kinase proteins that form a subfamily of receptor serine/threonine kinases. Mutations in this gene are associated with hemorrhagic telangiectasia type 2, also known as Rendu-Osler-Weber syndrome 2.
Specifications

Specifications

ACVRL1
Polyclonal
Unconjugated
ACVRL1
Liquid
ACVRL1
Synthetic peptide corresponding to a region within amino acids 441 and 503 of Human Activin A Receptor Type II-like 1
Antigen affinity chromatography
RUO
Antibody
Polyclonal
Human, Mouse
Immunohistochemistry (Paraffin), Western Blot
1 mg/mL
PBS with 20% glycerol and 0.01% thimerosal; pH 7
P37023, Q61288
ACVRLK1, ALK-1, ALK1, HHT, HHT2, ORW2, SKR3, TSR-I, TGF-B superfamily receptor type I, activin A receptor, type II-like kinase 1, activin receptor-like kinase 1, serine/threonine-protein kinase receptor R3
Rabbit
IgG
100 μL
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Primary
11482, 94
Documents
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