ACVR1 Sheep anti-Chicken, Polyclonal, Invitrogen
Sheep Polyclonal Antibody
Manufacturer: Invitrogen PA112641
The TGF-beta superfamily of ligands exerts its biological activity by binding to heteromeric receptor complexes two types (I and II) of the serine/threonine kinases. ALK1, like the other type I receptors, contains a cysteine rich domain with conserved cysteine spacing in the extracellular region and a glycine and serine rich domain preceding the kinase domain. The reduced human ALK1 monomer has a calculated molecular mass of approximately 37.3 kDa. Due to glycoslyation, the recombinant human protein migrates as a 50-55kDa protein in SDS-PAGE under reducing conditions. Human and mouse ALK1 share approximately 71% amino acid sequence identity in their extracellular domains. ALK1 is highly expressed in endothelial cells and other vascular tissues.
|PBS with 0.08% sodium azide|
|ACTRI, ACVRLK2, ACVR1, SKR1|
|-20° C, Avoid Freeze/Thaw Cycles|
|Recombit protein corresponding to the extracellular domain of chicken ALK2.|
|Ammonium sulfate precipitation|
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