ACVRL1 Goat anti-Human, Polyclonal, Invitrogen™
Goat Polyclonal Antibody
Supplier: Thermo Scientific PA120176
PA1-20176 detects Activin Receptor-Like Kinase 1 in human samples. PA1-20176 has been successfully used in ELISA and Western blot procedures. The PA1-20176 immunogen is a recombit fragment of human Activin Receptor-Like Kinase 1.The TGF-beta superfamily of ligands exerts its biological activity by binding to heteromeric receptor complexes two types (I and II) of the serine/threonine kinases. ALK1, like the other type I receptors, contains a cysteine rich domain with conserved cysteine spacing in the extracellular region and a glycine and serine rich domain preceding the kinase domain. The reduced human ALK1 monomer has a calculated molecular mass of approximately 37.3 kDa. Due to glycoslyation, the recombit human protein migrates as a 50-55 kDa protein in SDS-PAGE under reducing conditions. Human and mouse ALK1 share approximately 71% amino acid sequence identity in their extracellular domains. ALK1 is highly expressed in endothelial cells and other vascular tissues.
|Recombit fragment of human Activin Receptor-Like Kinase 1.
|ELISA, Western Blot
|ACVRLK1, ALK-1, ALK1, HHT, HHT2, ORW2, SKR3, TSR-I
|Antigen affinity chromatography
|Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
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