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ACVRL1 Goat anti-Human, Polyclonal, Invitrogen™

Goat Polyclonal Antibody

Supplier:  Thermo Scientific PA120176

Catalog No. PIPA120176

Item Discontinued This item has been discontinued by the supplier and is no longer available. Please reach out to your sales representative.


Description

Description

PA1-20176 detects Activin Receptor-Like Kinase 1 in human samples. PA1-20176 has been successfully used in ELISA and Western blot procedures. The PA1-20176 immunogen is a recombit fragment of human Activin Receptor-Like Kinase 1.

The TGF-beta superfamily of ligands exerts its biological activity by binding to heteromeric receptor complexes two types (I and II) of the serine/threonine kinases. ALK1, like the other type I receptors, contains a cysteine rich domain with conserved cysteine spacing in the extracellular region and a glycine and serine rich domain preceding the kinase domain. The reduced human ALK1 monomer has a calculated molecular mass of approximately 37.3 kDa. Due to glycoslyation, the recombit human protein migrates as a 50-55 kDa protein in SDS-PAGE under reducing conditions. Human and mouse ALK1 share approximately 71% amino acid sequence identity in their extracellular domains. ALK1 is highly expressed in endothelial cells and other vascular tissues.
TRUSTED_SUSTAINABILITY
Specifications

Specifications

ACVRL1
Polyclonal
Unconjugated
P37023
ACVRL1
Recombit fragment of human Activin Receptor-Like Kinase 1.
25 μg
Primary
Human
Antibody
IgG
ELISA, Western Blot
0.1 mg/mL
ACVRL1
ACVRLK1, ALK-1, ALK1, HHT, HHT2, ORW2, SKR3, TSR-I
Goat
Antigen affinity chromatography
RUO
94
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Liquid
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Recommendations

SDS
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