BAF53A Mouse anti-Human, Clone: 3C4, Invitrogen
Mouse Monoclonal Antibody
Manufacturer: Invitrogen MA518344
Peptide Sequence: MVVERDDGST LMEIDGDKGK QGGPTYYIDT NALRVPRENM EAISPLKNGM VEDWDSFQAI LDHTYKMHVK SEASLHPVLMThis gene encodes a family member of actin-related proteins (ARPs), which share significant amino acid sequence identity to conventional actins. Both actins and ARPs have an actin fold, which is an ATP-binding cleft, as a common feature. The ARPs are involved in diverse cellular processes, including vesicular transport, spindle orientation, nuclear migration and chromatin remodeling. This gene encodes a 53 kDa subunit protein of the BAF (BRG1/brm-associated factor) complex in mammals, which is functionally related to SWI/SNF complex in S. cerevisiae and Drosophila; the latter is thought to facilitate transcriptional activation of specific genes by antagonizing chromatin-mediated transcriptional repression. Together with beta-actin, it is required for maximal ATPase activity of BRG1, and for the association of the BAF complex with chromatin/matrix. Three transcript variants that encode two different protein isoforms have been described.
|PBS with no preservative; pH 7.4|
|ACTL6A, ACTL6B, BAF53A, BAF53B, ACTL6, BAF53a, BAF53b, actin-like 6A, actin-like 6B, hArpN alpha, actin-related protein, ACTL6A, ACTL6B, 53 kDa BRG1-associated factor B, ARPN-BETA, MGC5382 Arp4, INO80K, BAF complex 53 kDa subunit, BAF53, BRG1-associated factor, INO80 complex subunit K, actin-related protein 4, hArpN beta|
|-20° C, Avoid Freeze/Thaw Cycles|
|ELISA, Western Blot|
|ACTL6A (NP_817126, 1 a.a. ∽ 80 a.a) partial recombit protein with GST tag. MW of the GST tag alone is 26 KDa.|
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