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Actin-like 7A Rabbit anti-Human, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA523971

Catalog No. PIPA523971

This item has been discontinued by the manufacturer and is no longer available. Please call customer service for assistance: 1-800-766-7000.


Description

Description

This antibody is predicted to react with non-human primate based on sequence homology.

ACTL7A is a member of a family of actin-related proteins (ARPs) which share significant amino acid sequence identity to conventional actins. Both actins and ARPs have an actin fold, which is an ATP-binding cleft, as a common feature. The ARPs are involved in diverse cellular processes, including vesicular transport, spindle orientation, nuclear migration and chromatin remodeling. ACTL7A (ACTL7A), and related gene, ACTL7B, are intronless, and are located approximately 4 kb apart in a head-to-head orientation within the familial dysautonomia candidate region on 9q31. Based on mutational analysis of the ACTL7A gene in patients with this disorder, it was concluded that it is unlikely to be involved in the pathogenesis of dysautonomia. The ACTL7A gene is expressed in a wide variety of adult tissues, however, its exact function is not known.
Specifications

Specifications

Actin-like 7A
Polyclonal
PBS with 0.09% sodium azide
Q9Y615
actin-like 7-alpha, actin-like protein 7A, actin-like-7-alpha
Rabbit
IgG
400 μL
-20° C, Avoid Freeze/Thaw Cycles
Primary
10881
Western Blot
Unconjugated
ACTL7A
Liquid
ACTL7A
KLH conjugated synthetic peptide between 41-67 amino acids from the N-terminal region of human ACTL7A
Antigen affinity chromatography
RUO
Antibody
Polyclonal
Human
Documents
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