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ADAM15 Rabbit anti-Human, Mouse, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA527459

Catalog No. PIPA527459


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Description

Description

PA5-27459 targets ADAM15 in IHC (P) and WB applications and shows reactivity with Human and mouse samples. The PA5-27459 immunogen is recombit fragment corresponding to a region within amino acids 1 and 255 of Human ADAM15. Store product as a concentrated solution. Centrifuge briefly prior to opening the vial. For short-term storage (1-2 weeks), product can be stored at 4°C. For long-term storage, aliquot and store product at -20° C or below, avioiding multiple freeze-thaw cycles.

The protein encoded by this gene is a member of the ADAM (a disintegrin and metalloproteinase) protein family. ADAM family members are type I transmembrane glycoproteins known to be involved in cell adhesion and proteolytic ectodomain processing of cytokines and adhesion molecules. This protein contains multiple functional domains including a zinc-binding metalloprotease domain, a disintegrin-like domain, as well as a EGF-like domain. Through its disintegrin-like domain, this protein specifically interacts with the integrin beta chain, beta 3. It also interacts with Src family protein-tyrosine kinases in a phosphorylation-dependent manner, suggesting that this protein may function in cell-cell adhesion as well as in cellular signaling. Multiple alternatively spliced transcript variants encoding distinct isoforms have been observed.
Specifications

Specifications

ADAM15
Polyclonal
Unconjugated
ADAM15
Liquid
ADAM15
Recombit fragment corresponding to a region within amino acids 1 and 255 of Human ADAM15
Antigen affinity chromatography
RUO
Antibody
Polyclonal
Human, Mouse
Immunohistochemistry (Paraffin), Western Blot
0.347 mg/mL
PBS with 10% glycerol and 0.01% thimerosal; pH 7
Q13444, O88839
MDC15, ADAM 15, MDC-15, a disintegrin and metalloproteinase domain 15 (metargidin), disintegrin and metalloproteinase domain-containing protein 15, metalloprotease RGD disintegrin protein, metalloproteinase-like, disintegrin-like, and cysteine-rich protein 15
Rabbit
IgG
100 μL
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Primary
11490, 8751
Documents
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