ADAM15 Rabbit anti-Human, Mouse, Polyclonal, Invitrogen
Rabbit Polyclonal Antibody
Manufacturer: Invitrogen PA527459
PA5-27459 targets ADAM15 in IHC (P) and WB applications and shows reactivity with Human and mouse samples. The PA5-27459 immunogen is recombit fragment corresponding to a region within amino acids 1 and 255 of Human ADAM15. Store product as a concentrated solution. Centrifuge briefly prior to opening the vial. For short-term storage (1-2 weeks), product can be stored at 4°C. For long-term storage, aliquot and store product at -20° C or below, avioiding multiple freeze-thaw cycles.The protein encoded by this gene is a member of the ADAM (a disintegrin and metalloproteinase) protein family. ADAM family members are type I transmembrane glycoproteins known to be involved in cell adhesion and proteolytic ectodomain processing of cytokines and adhesion molecules. This protein contains multiple functional domains including a zinc-binding metalloprotease domain, a disintegrin-like domain, as well as a EGF-like domain. Through its disintegrin-like domain, this protein specifically interacts with the integrin beta chain, beta 3. It also interacts with Src family protein-tyrosine kinases in a phosphorylation-dependent manner, suggesting that this protein may function in cell-cell adhesion as well as in cellular signaling. Multiple alternatively spliced transcript variants encoding distinct isoforms have been observed.
|Recombit fragment corresponding to a region within amino acids 1 and 255 of Human ADAM15|
|Antigen affinity chromatography|
|Immunohistochemistry (Paraffin), Western Blot|
|PBS with 10% glycerol and 0.01% thimerosal; pH 7|
|MDC15, ADAM 15, MDC-15, a disintegrin and metalloproteinase domain 15 (metargidin), disintegrin and metalloproteinase domain-containing protein 15, metalloprotease RGD disintegrin protein, metalloproteinase-like, disintegrin-like, and cysteine-rich protein 15|
|Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
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