ADAM17 Goat anti-Human, Polyclonal, Invitrogen™
Goat Polyclonal Antibody
Manufacturer: Invitrogen PA19003
This antibody is predicted to react with mouse and rat based on sequence homology.This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biologic processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. The protein encoded by this gene functions as a tumor necrosis factor-alpha converting enzyme; binds mitotic arrest deficient 2 protein; and also plays a prominent role in the activation of the Notch signaling pathway.
|Synthetic peptide corresponding to the C terminus amino acids LQRQNRVDSKETEC.|
|Antigen affinity chromatography|
|Immunohistochemistry, Western Blot|
|TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3|
|A disintegrin and metalloproteinase domain 17, TNF-alpha-converting enzyme, TNF-alpha convertase, Snake venom-like protease, CD156b antigen, CSVP, TACE|
|-20° C, Avoid Freeze/Thaw Cycles|
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