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ADAM17 Rabbit anti-Human, Mouse, Rat, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA527395

Catalog No. PIPA527395


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Description

Description

PA5-27395 targets ADAM17 in IHC (P) and WB applications and shows reactivity with Human samples. The PA5-27395 immunogen is recombit fragment corresponding to a region within amino acids 668 and 824 of Human ADAM17. Store product as a concentrated solution. Centrifuge briefly prior to opening the vial. For short-term storage (1-2 weeks), product can be stored at 4°C. For long-term storage, aliquot and store product at -20° C or below, avioiding multiple freeze-thaw cycles.

This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biologic processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. The protein encoded by this gene functions as a tumor necrosis factor-alpha converting enzyme; binds mitotic arrest deficient 2 protein; and also plays a prominent role in the activation of the Notch signaling pathway.
Specifications

Specifications

ADAM17
Polyclonal
Unconjugated
ADAM17
Liquid
ADAM17
Recombit fragment corresponding to a region within amino acids 668 and 824 of Human ADAM17
Antigen affinity chromatography
RUO
Antibody
Polyclonal
Human, Mouse, Rat
Immunohistochemistry (Paraffin), Western Blot
1 mg/mL
PBS with 40% glycerol and 0.01% thimerosal; pH 7
P78536, Q9Z0F8, Q9Z1K9
A disintegrin and metalloproteinase domain 17, TNF-alpha-converting enzyme, TNF-alpha convertase, Snake venom-like protease, CD156b antigen, CSVP, TACE
Rabbit
IgG
100 μL
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Primary
11491, 57027, 6868
Documents
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