ADAMTS13 Mouse anti-Human, Clone: 442323, Invitrogen
Mouse Monoclonal Antibody
Manufacturer: Invitrogen MA524167
In direct ELISAs and Western blots, no cross-reactivity with recombit human (rh) ADAMTS1, rhADAMTS4, rhADAMTS5, or rhADAMTS-L1.2 is observed. Reconstitute at 0.5 mg/mL in sterile PBS.ADAMTS13 is a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motif) protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The enzyme is the von Willebrand Factor (vWF)-cleaving protease, which is responsible for cleaving at the site of Tyr842-Met843 of the vWF molecule. A deficiency of this enzyme is associated with thrombotic thrombocytopenic purpura.
|PBS with 5% trehalose and No Preservative|
|von Willebrand factor-cleaving protease, vWF-cleaving protease, vWF-CP, A disintegrin and metalloproteinase with thrombospondin motifs 13, ADAMTS-13, ADAM-TS 13, ADAM-TS13, ADAMTS13, C9orf8|
|-20° C, Avoid Freeze/Thaw Cycles|
|Flow Cytometry, Immunoprecipitation, Western Blot|
|CHO-derived recombit human ADAMTS13 isoform 1 Gln34-Trp688 (predicted)|
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