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ADAMTS13 Mouse anti-Human, Clone: 442323, Invitrogen™

Mouse Monoclonal Antibody

Manufacturer:  Invitrogen MA524167

Catalog No. PIMA524167


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Description

Description

In direct ELISAs and Western blots, no cross-reactivity with recombit human (rh) ADAMTS1, rhADAMTS4, rhADAMTS5, or rhADAMTS-L1.2 is observed. Reconstitute at 0.5 mg/mL in sterile PBS.

ADAMTS13 is a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motif) protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The enzyme is the von Willebrand Factor (vWF)-cleaving protease, which is responsible for cleaving at the site of Tyr842-Met843 of the vWF molecule. A deficiency of this enzyme is associated with thrombotic thrombocytopenic purpura.
Specifications

Specifications

ADAMTS13
Monoclonal
0.5 mg/mL
PBS with 5% trehalose and No Preservative
Q76LX8
von Willebrand factor-cleaving protease, vWF-cleaving protease, vWF-CP, A disintegrin and metalloproteinase with thrombospondin motifs 13, ADAMTS-13, ADAM-TS 13, ADAM-TS13, ADAMTS13, C9orf8
Mouse
IgG1
100 μg
-20° C, Avoid Freeze/Thaw Cycles
Primary
11093
Flow Cytometry, Immunoprecipitation, Western Blot
442323
Unconjugated
ADAMTS13
Lyophilized
ADAMTS13
CHO-derived recombit human ADAMTS13 isoform 1 Gln34-Trp688 (predicted)
Protein A/G
RUO
Antibody
Monoclonal
Human
Documents
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