ADAMTS13 Rabbit anti-Human, Polyclonal, Invitrogen
Rabbit Polyclonal Antibody
Manufacturer: Invitrogen PA514339
DescriptionADAMTS13 is a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motif) protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The enzyme is the von Willebrand Factor (vWF)-cleaving protease, which is responsible for cleaving at the site of Tyr842-Met843 of the vWF molecule. A deficiency of this enzyme is associated with thrombotic thrombocytopenic purpura.
|PBS with 0.09% sodium azide|
|von Willebrand factor-cleaving protease; vWF-cleaving protease; vWF-CP; A disintegrin and metalloproteinase with thrombospondin motifs 13; ADAMTS-13; ADAM-TS 13; ADAM-TS13; ADAMTS13; C9orf8|
|-20° C, Avoid Freeze/Thaw Cycles|
|Immunohistochemistry, Western Blot|
|KLH conjugated synthetic peptide between 829-858 amino acids from the central region of human ADAMTS13|
|Antigen affinity chromatography|
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