ADAMTS2 Rabbit anti-Human, Polyclonal, Invitrogen
Rabbit Polyclonal Antibody
Manufacturer: Invitrogen PA125179
PA1-25179 detects ADAMTS2 from human samples. PA1-25179 has been successfully used in Western blot procedures. The PA1-25179 immunogen is a synthetic peptide corresponding to the C-terminal domain of human ADAMTS2. Store product as a concentrated solution. Centrifuge briefly prior to opening the vial. For short-term storage (1-2 weeks), product can be stored at 4°C. For long-term storage, aliquot and store product at -20° C or below, avioiding multiple freeze-thaw cycles.This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The enzyme encoded by this gene excises the N-propeptide of type I, type II and type V procollagens. Mutations in this gene cause Ehlers-Danlos syndrome type VIIC, a recessively inherited connective-tissue disorder. Alternative splicing results in two transcript variants. The short transcript encodes a protein which has no significant procollagen N-peptidase activity.
|Synthetic peptide corresponding to the C-terminal domain of human ADAMTS2.|
|Antigen affinity chromatography|
|PBS with 50% glycerol and 0.05% sodium azide|
|ADAM-TS2, ADAMTS-3, NPI, PCINP, PCPNI, hPCPNI|
|Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
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