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ADAMTS2 Rabbit anti-Human, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA125180

Catalog No. PA125180


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Description

Description

PA1-25180 detects ADAMTS2 from human samples. PA1-25180 has been successfully used in Western blot procedures. The PA1-25180 immunogen is a synthetic peptide corresponding to the propeptide domain of human ADAMTS2. Store product as a concentrated solution. Centrifuge briefly prior to opening the vial. For short-term storage (1-2 weeks), product can be stored at 4°C. For long-term storage, aliquot and store product at -20° C or below, avioiding multiple freeze-thaw cycles.

This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The enzyme encoded by this gene excises the N-propeptide of type I, type II and type V procollagens. Mutations in this gene cause Ehlers-Danlos syndrome type VIIC, a recessively inherited connective-tissue disorder. Alternative splicing results in two transcript variants. The short transcript encodes a protein which has no significant procollagen N-peptidase activity.
Specifications

Specifications

ADAMTS2
Polyclonal
Unconjugated
ADAMTS2
Liquid
ADAMTS2
Synthetic peptide corresponding to the propeptide domain of human ADAMTS2.
Antigen affinity chromatography
RUO
Antibody
Polyclonal
Human
Western Blot
1 mg/mL
PBS with 50% glycerol and 0.05% sodium azide
O95450
ADAM-TS2, ADAMTS-3, NPI, PCINP, PCPNI, hPCPNI
Rabbit
IgG
50 μg
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Primary
9509
Documents
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