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Adenylate Kinase 1 Rabbit anti-Human, Mouse, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA528354

Catalog No. PIPA528354


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Description

Description

PA5-28354 targets Adenylate kinase 1 in WB applications and shows reactivity with Human and mouse samples. The PA5-28354 immunogen is recombit fragment corresponding to a region within amino acids 1 and 188 of Human Adenylate kinase 1. Store product as a concentrated solution. Centrifuge briefly prior to opening the vial. For short-term storage (1-2 weeks), product can be stored at 4°C. For long-term storage, aliquot and store product at -20° C or below, avioiding multiple freeze-thaw cycles.

Adenylate kinase is an enzyme involved in regulating the adenine nucleotide composition within a cell by catalyzing the reversible transfer of phosphate group among adinine nucleotides. Three isozymes of adenylate kinase have been identified in vertebrates, adenylate isozyme 1 (AK1), 2 (AK2) and 3 (AK3). AK1 is found in the cytosol of skeletal muscle, brain and erythrocytes, whereas AK2 and AK3 are found in the mitochondria of other tissues including liver and heart. AK1 was identified because of its association with a rare genetic disorder causing nonspherocytic hemolytic anemia where a mutation in the AK1 gene was found to reduce the catalytic activity of the enzyme.
Specifications

Specifications

Adenylate kinase 1
Polyclonal
Unconjugated
AK1
Liquid
AK1
Recombit fragment corresponding to a region within amino acids 1 and 188 of Human Adenylate kinase 1
Antigen affinity chromatography
RUO
Antibody
Polyclonal
Human, Mouse
Immunohistochemistry (Paraffin), Western Blot
0.4 mg/mL
0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7
P00568, Q9R0Y5
AK 1, ATP-AMP transphosphorylase 1, adenylate kinase isoenzyme 1, myokinase
Rabbit
IgG
100 μL
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Primary
11636, 203
Documents
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