ADRA1B Rabbit anti-Human, Polyclonal Antibody, Abnova™

Rabbit polyclonal antibody raised against synthetic peptide of ADRA1B.

Supplier:  Abnova Corporation PAB16419

Catalog No. 89-118-291

Description

Alpha-1-adrenergic receptors (alpha-1-ARs) are members of the G protein-coupled receptor superfamily. They activate mitogenic responses and regulate growth and proliferation of many cells. There are 3 alpha-1-AR subtypes: alpha-1A, -1B and -1D, all of which signal through the Gq/11 family of G-proteins and different subtypes show different patterns of activation. This gene encodes alpha-1B-adrenergic receptor, which induces neoplastic transformation when transfected into NIH 3T3 fibroblasts and other cell lines. Thus, this normal cellular gene is identified as a protooncogene. This gene comprises 2 exons and a single large intron of at least 20kb that interrupts the coding region. [provided by RefSeq

Specifications

• Antigen: ADRA1B
• Classification: Polyclonal
• Description: Rabbit polyclonal antibody raised against synthetic peptide of ADRA1B.
• Formulation: In PBS (0.09% sodium azide)
• Gene Accession No.: P35368
• Gene Symbols: ADRA1B
• Immunogen: A synthetic peptide (conjugated with KLH) corresponding to human ADRA1B.
• Quantity: 50 μg
• Primary or Secondary: Primary
• Test Specificity: C-terminal Cytoplasmic domain of human.
• Content And Storage: Store at 4°C. For long term storage store at -80°C.
  Aliquot to avoid repeated freezing and thawing.

• Applications: Immunohistochemistry (PFA fixed)
• Conjugate: Unconjugated
• Dilution: Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (10 ug/mL) The optimal working dilution should be determined by the end user.
• Gene: ADRA1B
• Gene Alias: ADRA1/ALPHA1BAR
• Host Species: Rabbit
• Purification Method: Immunoaffinity purification
• Regulatory Status: RUO
• Gene ID (Entrez): 147
• Target Species: Human
• Form: Liquid

For Research Use Only