alpha-1b Adrenergic Receptor Rabbit anti-Human, Polyclonal, Invitrogen
Rabbit Polyclonal Antibody
Manufacturer: Invitrogen PA526411
This antibody is predicted to react with bovine, mouse, rat and rabbit based on sequence homology.Alpha-1-adrenergic receptors (alpha-1-ARs) are members of the G protein-coupled receptor superfamily. They activate mitogenic responses and regulate growth and proliferation of many cells. There are 3 alpha-1-AR subtypes: alpha-1A, -1B and -1D, all of which signal through the Gq/11 family of G-proteins and different subtypes show different patterns of activation. This protein encodes alpha-1B-adrenergic receptor, which induces neoplastic transformation when transfected into NIH 3T3 fibroblasts and other cell lines. Thus, this normal cellular gene is identified as a protooncogene. This protein comprises 2 exons and a single large intron of at least 20 kb that interrupts the coding region.
|alpha-1b Adrenergic Receptor|
|PBS with 0.09% sodium azide|
|ADRA1, ALPHA1BAR, alpha-1B adrenergic receptor, alpha-1B adrenoceptor, alpha-1B adrenoreceptor, alpha-1B-adrenergic receptor|
|-20° C, Avoid Freeze/Thaw Cycles|
|Immunohistochemistry (Paraffin), Western Blot|
|KLH conjugated synthetic peptide between 270-297 amino acids from the central region of human ADRA1B|
|Antigen Affinity Chromatography, Protein A|
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