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AFP Rabbit anti-Human, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA511481

Catalog No. PIPA511481

This item has been discontinued by the manufacturer and is no longer available. Please call customer service for assistance: 1-800-766-7000.


Description

Description

AFP (Alpha Fetoprotein) is a major plasma protein produced by the yolk sac, intestinal tract and the liver during fetal life. AFP expression in adults is often associated with hepatoma or teratoma. However, hereditary persistence of AFP may also be found in individuals with no obvious pathology. The protein is thought to be the fetal counterpart of serum albumin, and AFP and albumin genes are present in tandem in the same transcriptional orientation on chromosome 4. AFP is found in monomeric, dimeric, and trimeric forms. AFP can also bind to copper ions, nickel ions, fatty acids and bilirubin. The level of AFP in amniotic fluid is used to measure renal loss of protein to screen for spina bifida and anencephaly. High level of serum AFP has been identified in patients with hepatocellular carcinomas (HCC), teratoblastoma, colorectal cancer, pancreatic cancer, and germ cell neoplasms.
Specifications

Specifications

AFP
Polyclonal
PBS with 0.09% sodium azide
P02771
Alpha-fetoprotein; Alpha-fetoglobulin; Alpha-1-fetoprotein; AFP; HPAFP
Rabbit
IgG
400 μL
-20° C, Avoid Freeze/Thaw Cycles
Primary
174
Immunohistochemistry, Western Blot
Unconjugated
AFP
Liquid
AFP
KLH conjugated synthetic peptide between 300-329 amino acids from the central region of human AFP
Antigen affinity chromatography
RUO
Antibody
Polyclonal
Human
Documents
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