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AIM Rabbit anti-Human, Mouse, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA520243

Catalog No. PIPA520243


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Description

Description

A suggested positive control is human lymph node tissue lysate. PA5-20243 can be used with blocking peptide PEP-0362.

Apoptosis inhibitor of macrophages (AIM) is a member of the scavenger receptor cysteine-rich domain superfamily (SRCR-SF) initially identified as an inducible cell surface ligand of CD5. It was shown that AIM functions in the thymus as the inducer of resistance to apoptosis within CD4+/CD8+ thymocytes and as the supporter of the viability of these cells before thymic selection. AIM was also shown to support macrophage survival and enhance their phagocytic function. More recent experiments using recombit AIM significantly inhibited apoptosis of NKT and T cells obtained from C. parvum-stimulated livers in vitro, suggesting that AIM functions to induce resistance to apoptosis in these cells and supports host defense against inflammation during infection.
Specifications

Specifications

AIM
Polyclonal
Unconjugated
CD5L
Liquid
CD5L
A 16 amino acid peptide near the amino terminus of human AIM.
Antigen affinity chromatography
RUO
Antibody
Polyclonal
Human, Mouse
Immunocytochemistry, Immunofluorescence, Immunohistochemistry, Western Blot
1 mg/mL
PBS with 0.02% sodium azide
O43866, Q9QWK4
UNQ203/PRO229, AIM, API6, PRO229, SP-ALPHA, Spalpha; CD5 antigen-like; CD5 antigen-like (scavenger receptor cysteine rich family); CT-2; apoptosis inhibitor 6; igM-associated peptide
Rabbit
IgG
100 μg
Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
Primary
11801, 922
Documents
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