AKR1B10 Rabbit anti-Human, Mouse, Rat, Polyclonal, Invitrogen
Rabbit Polyclonal Antibody
Manufacturer: Invitrogen PA141259
AKR1B10, a 316aa protein, catalyzes efficient reduction of aliphatic and aromatic aldehydes. It the first cytosolic NADP (H)-dependent retinal reductase described in humans and is characterized by the presence of a novel NADP binding motif. Due to its ability to convert glucose to sorbitol, AKR1B10 may have a role in development of secondary diabetic complications. It is abundantly expressed in adrenal gland, small intestine and colon, with lower levels in liver, thymus, prostate, testis, and skeletal muscle and its levels are up regulated in certain cancers such as hepatocellular carcinoma.This antibody is predicted to react with chimpanzee samples based on sequence homology.Suggested positive control: human, mouse or rat liver tissue lysate.
|PBS with 0.2% gelatin and 0.05% sodium azide|
|Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
|296972, 57016, 67861|
|Synthetic peptide corresponding to residues 100-200 of human AKR1B10.|
|Human, Mouse, Rat|
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