AKR1C3 Rabbit anti-Human, Rat, Polyclonal, Invitrogen
Rabbit Polyclonal Antibody
Manufacturer: Invitrogen PA528065
PA5-28065 targets AKR1C3 in IF, ICC, IHC (P), and WB applications and shows reactivity with human and rat samples. The PA5-28065 immunogen is synthetic peptide corresponding to a region within amino acids 261 and 323 of Human AKR1C3. Store product as a concentrated solution. Centrifuge briefly prior to opening the vial. For short-term storage (1-2 weeks), product can be stored at 4°C. For long-term storage, aliquot and store product at -20° C or below, avioiding multiple freeze-thaw cycles.AKR1C3 a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. These enzymes catalyze the conversion of aldehydes and ketones to their corresponding alcohols by utilizing NADH and/or NADPH as cofactors. The enzymes display overlapping but distinct substrate specificity. This enzyme catalyzes the reduction of prostaglandin (PG) D2, PGH2 and phethrenequinone (PQ), and the oxidation of 9-alpha,11-beta-PGF2 to PGD2. It may play an important role in the pathogenesis of allergic diseases such as asthma, and may also have a role in controlling cell growth and/or differentiation. This gene shares high sequence identity with three other gene members and is clustered with those three genes at chromosome 10p15-p14.
|Synthetic peptide corresponding to a region within amino acids 261 and 323 of Human AKR1C3|
|Antigen affinity chromatography|
|Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot|
|PBS with 40% glycerol and 0.01% thimerosal; pH 7|
|DD3, DDX, HA1753, HAKRB, HAKRe, HSD17B5, PGFS, hluPGFS, 3-alpha-HSD type II, brain, aldo-keto reductase family 1 member C3, chlordecone reductase homolog HAKRb, dihydrodiol dehydrogenase 3, dihydrodiol dehydrogenase X, indanol dehydrogenase, prostaglandin F synthase, testosterone 17-beta-dehydrogenase 5, trans-1,2-dih|
|Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
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