AKT1 Mouse anti-Human, Mouse, Rat, APC, Clone: 281046, Invitrogen
Mouse Monoclonal Antibody
Manufacturer: Invitrogen MA523646
DescriptionAKT, also known as protein kinase B (PKB), is a 57 kDa serine/threonine protein kinase. There are three mammalian isoforms of Akt: AKT1 (PKB alpha), AKT2 (PKB beta) and AKT3 (PKB gamma) with AKT2 and AKT3 being approximately 82% identical with the AKT1 isoform. Each isoform has a pleckstrin homology (PH) domain, a kinase domain and a carboxy terminal regulatory domain. AKT was originally cloned from the retrovirus AKT8, and is a key regulator of many signal transduction pathways. Its tight control over cell proliferation and cell viability are manifold, overexpression or inappropriate activation of AKT has been seen in many types of cancer.
|E. coli-derived recombit human Akt1 Ser2-Ala480|
|Human, Mouse, Rat|
|Buffered saline solution with BSA and 0.09% sodium azide|
|P31749, P31750, P47196|
|RAC-alpha serine/threonine-protein kinase, Protein kinase B, PKB, Protein kinase B alpha, PKB alpha, Proto-oncogene c-Akt, RAC-PK-alpha, AKT1, PKB, RAC, PKB alpha, RAC-beta serine/threonine-protein kinase, Protein kinase Akt-3, Protein kinase B gamma, PKB gamma, RAC-PK-gamma, STK-2, AKT3, PKBG, PKB gamma|
|4° C, store in dark, DO NOT FREEZE!|
|11651, 207, 24185|
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