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AKT1 Mouse anti-Human, Mouse, Rat, APC, Clone: 281046, Invitrogen™

Mouse Monoclonal Antibody

Manufacturer:  Invitrogen MA523646

Catalog No. PIMA523646


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Description

Description

AKT, also known as protein kinase B (PKB), is a 57 kDa serine/threonine protein kinase. There are three mammalian isoforms of Akt: AKT1 (PKB alpha), AKT2 (PKB beta) and AKT3 (PKB gamma) with AKT2 and AKT3 being approximately 82% identical with the AKT1 isoform. Each isoform has a pleckstrin homology (PH) domain, a kinase domain and a carboxy terminal regulatory domain. AKT was originally cloned from the retrovirus AKT8, and is a key regulator of many signal transduction pathways. Its tight control over cell proliferation and cell viability are manifold, overexpression or inappropriate activation of AKT has been seen in many types of cancer.
Specifications

Specifications

AKT1
Monoclonal
APC
AKT1
Liquid
AKT1
E. coli-derived recombit human Akt1 Ser2-Ala480
Protein A/G
RUO
Antibody
Monoclonal
Human, Mouse, Rat
Flow Cytometry
281046
Buffered saline solution with BSA and 0.09% sodium azide
P31749, P31750, P47196
RAC-alpha serine/threonine-protein kinase, Protein kinase B, PKB, Protein kinase B alpha, PKB alpha, Proto-oncogene c-Akt, RAC-PK-alpha, AKT1, PKB, RAC, PKB alpha, RAC-beta serine/threonine-protein kinase, Protein kinase Akt-3, Protein kinase B gamma, PKB gamma, RAC-PK-gamma, STK-2, AKT3, PKBG, PKB gamma
Mouse
IgG2B
100 Tests
4° C, store in dark, DO NOT FREEZE!
Primary
11651, 207, 24185
Documents
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