Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More

ALDH3A2 Rabbit anti-Human, Mouse, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA520603

Catalog No. PIPA520603


Add to cart

Description

Description

A suggested positive control is mouse liver tissue lysate. PA5-20603 can be used with blocking peptide PEP-0723.

Aldh3A2 is a member of the aldehyde dehydrogenase superfamily, a group of NAD(P)(+)-dependent enzymes that catalyze the oxidation of a wide spectrum of aliphatic and aromatic aldehydes. Aldehyde dehydrogenase enzymes are thought to play a major role in the detoxification of aldehydes generated by alcohol metabolism and lipid peroxidation. Aldh3A2 catalyzes the oxidation of long-chain aliphatic aldehydes to fatty acids. Mutations in the Aldh3A2 gene cause Sjogren-Larrson syndrome, an inherited neurocutaneous disorder. Patients with this disorder display ichthyosis, mental retardation and spastic diplegia. The pathogenesis of the cutaneous and neurological symptoms is thought to result from abnormal lipid accumulation in the membranes of skin and brain, the formation of aldehyde Schiff base adducts with amine-containing lipids or proteins, or defective eicosanoid metabolism.
Specifications

Specifications

Aldh3A2
Polyclonal
Unconjugated
ALDH3A2
Liquid
ALDH3A2
A 14 amino acid peptide near the carboxy terminus of the human Aldh3A2.
Antigen affinity chromatography
RUO
Antibody
Polyclonal
Human, Mouse
Western Blot
1 mg/mL
PBS with 0.02% sodium azide
P51648, P47740
ALDH10, FALDH, SLS; aldehyde dehydrogenase 10; aldehyde dehydrogenase family 3 member A2; fatty aldehyde dehydrogenase; microsomal aldehyde dehydrogenase
Rabbit
IgG
100 μg
Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
Primary
11671, 224
Documents
Provide Content Correction

We continue to work to improve your shopping experience and your feedback regarding this content is very important to us. Please use the form below to provide feedback related to the content on this product.

Product Title

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.

Cancel Submit