ALDH5A1 Rabbit anti-Human, Mouse, Rat, Polyclonal, Invitrogen
Rabbit Polyclonal Antibody
Manufacturer: Invitrogen PA520609
A suggested positive control is mouse liver tissue lysate. PA5-20609 can be used with blocking peptide PEP-0729.Aldh5A1 is a member of the aldehyde dehydrogenase superfamily, a group of NAD(P)(+)-dependent enzymes that catalyze the oxidation of a wide spectrum of aliphatic and aromatic aldehydes. Aldehyde dehydrogenase enzymes are thought to play a major role in the detoxification of aldehydes generated by alcohol metabolism and lipid peroxidation. Aldh5A1 is a mitochondrial NAD(+)-dependent succinic semialdehyde dehydrogenase. A deficiency of this enzyme, known as 4-hydroxybutyricaciduria, results in a disorder of the neurotransmitter 4-aminobutyric acid (GABA). Symptoms usually include static encephalopathy, associated with developmental delays, hypotonia, ataxia, speech defects, and seizures. At least two isoforms of Aldh5A1 are known to exist.
|a 22 amino acid peptide near the carboxy terminus of the human Aldh5A1.|
|Antigen affinity chromatography|
|Human, Mouse, Rat|
|PBS with 0.02% sodium azide|
|P51649, Q8BWF0, P51650|
|SSADH, SSDH; NAD(+)-dependent succinic semialdehyde dehydrogenase; aldehyde dehydrogenase family 5 member A1; mitochondrial succinate semialdehyde dehydrogenase; succinate-semialdehyde dehydrogenase, mitochondrial|
|Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C|
|214579, 291133, 7915|
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