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ALDH5A1 Rabbit anti-Human, Mouse, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA529096

Catalog No. PIPA529096


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Description

Description

PA5-29096 targets ALDH5A1 in IF, IHC (P), and WB applications and shows reactivity with Human and mouse samples. The PA5-29096 immunogen is recombit protein fragment corresponding to a region within amino acids 85 and 324 of Human ALDH5A1. Store product as a concentrated solution. Centrifuge briefly prior to opening the vial. For short-term storage (1-2 weeks), product can be stored at 4°C. For long-term storage, aliquot and store product at -20° C or below, avioiding multiple freeze-thaw cycles.

This protein belongs to the aldehyde dehydrogenase family of proteins. This gene encodes a mitochondrial NAD(+)-dependent succinic semialdehyde dehydrogenase. A deficiency of this enzyme, known as 4-hydroxybutyricaciduria, is a rare inborn error in the metabolism of the neurotransmitter 4-aminobutyric acid (GABA). In response to the defect, physiologic fluids from patients accumulate GHB, a compound with numerous neuromodulatory properties. Two transcript variants encoding distinct isoforms have been identified for this gene.
Specifications

Specifications

ALDH5A1
Polyclonal
Unconjugated
ALDH5A1
Liquid
ALDH5A1
Recombit protein fragment corresponding to a region within amino acids 85 and 324 of Human ALDH5A1
Antigen affinity chromatography
RUO
Antibody
Polyclonal
Human, Mouse
Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
1 mg/mL
0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7
P51649, Q8BWF0
SSADH, SSDH, NAD(+)-dependent succinic semialdehyde dehydrogenase, aldehyde dehydrogenase family 5 member A1, mitochondrial succinate semialdehyde dehydrogenase, succinate-semialdehyde dehydrogenase, mitochondrial
Rabbit
IgG
100 μL
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Primary
214579, 7915
Documents
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