ALOXE3 Rabbit anti-Human, Mouse, Polyclonal, Invitrogen
Rabbit Polyclonal Antibody
Manufacturer: Invitrogen PA523953
DescriptionALOXE3 is a member of the lipoxygenase family, which are catabolized by arachidonic acid-derived compounds. The encoded enzyme is a hydroperoxide isomerase that synthesizes a unique type of epoxy alcohol (8R-hydroxy-11R,12R-epoxyeicosa-5Z,9E,14Z-trienoic acid) from 12R-hydroperoxyeicosatetraenoic acid (12R-HPETE). This epoxy alcohol can activate the the nuclear receptor peroxisome proliferator-activated receptor alpha (PPARalpha), which is implicated in epidermal differentiation. Loss of function of the enzyme encoded by this gene results in ichthyosis, implicating the function of this gene in the differentiation of human skin.
|PBS with 0.09% sodium azide|
|E-LOX, eLOX3, e-LOX-3, epidermal lipoxygenase, epidermis-type lipoxygenase 3|
|-20° C, Avoid Freeze/Thaw Cycles|
|KLH conjugated synthetic peptide between 223-252 amino acids from the central region of human ALOXE3|
|Protein A, Antigen Affinity Chromatography|
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