A2M Chicken anti-Human, Mouse, Rat, Polyclonal, Invitrogen
Chicken Polyclonal Antibody
Manufacturer: Invitrogen PA129889
PA1-29889 detects alpha 2 Macroglobulin from rat, human, mouse samples. PA1-29889 has been successfully used in Western blot & ELISA applications. The PA1-29889 immunogen is full length protein (Human). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial. For short-term storage (1-2 weeks), product can be stored at 4°C. For long-term storage, aliquot and store product at -20° C or below, avioiding multiple freeze-thaw cycles.Alpha 2-Macroglobulin (a2M), is a ~720-kDa homotetrameric glycoprotein composed of four identical ~180 kDa subunits. aAlpha 2M shares with other alpha-macroglobulins, like the complement components C3 and C4 and the pregcy zone protein PZP, an extraordinary binding capacity for a variety of ligands. This allows the alpha-macroglobulins to serve as humoral defense barriers against foreign peptides in the plasma. Alpha 2M interacts and captures virtually any proteinase, often referred to as a panprotease inhibitor. In the brain of Alzheimer ft.s disease (AD) patients, Alpha 2M also has been localized to diffuse amyloid plaques, supporting an important role for alpha 2M in AD etiopathology.
|Full length protein (Human).|
|Antigen affinity chromatography|
|Human, Mouse, Rat|
|ELISA, Western Blot|
|PBS with 0.02% sodium azide|
|P01023, Q6GQT1, P06238|
|CPAMD5, DKFZp779B086, FWP007, S863-7|
|Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
|2, 232345, 24153|
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