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alpha-2b Adrenergic Receptor Mouse anti-Mouse, Rat, Clone: 5G10, Invitrogen™

Mouse Monoclonal Antibody

Manufacturer:  Invitrogen MA112721

Catalog No. 01-674-051


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Description

Description

A suggested positive control for this product is MDCK cells transfected with rat alpha2B adrenergic receptors.

The rat alpha 2b adrenergic receptor is a G protein coupled receptor which acts through Gi2 and is responsible for Cellular communication and signal transduction. These receptors are linked to pertussis toxin-sensitive G proteins. Agonist binding leads to inhibition of adenylyl cyclase, inhibition of Ca(2+) channels and activation of K(+) channels. Recently, three distinct subtypes of alpha(2)-AR were described, alpha(2A)-AR, alpha(2B)-AR and alpha(2C)-AR. At present, it is unknown which of these alpha(2)-AR subtype(s) may regulate insulin secretion.
Specifications

Specifications

alpha-2b Adrenergic Receptor
Monoclonal
0.8 mg/mL
PBS with 0.08% sodium azide
P30545, P19328
ADRA2B
Synthetic peptide corresponding to the third intracellular loop of rat alpha 2b adrenergic receptor.
Protein A/G
RUO
Antibody
Monoclonal
Mouse, Rat
Immunohistochemistry, Western Blot
5G10
Unconjugated
Adra2b
Liquid
Mouse
IgG1
100 μg
-20° C, Avoid Freeze/Thaw Cycles
Primary
11552, 24174
Documents
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