alpha-2c Adrenergic Receptor Rabbit anti-Human, Polyclonal, Invitrogen™
Rabbit Polyclonal Antibody
Supplier: Thermo Scientific PA132862
PA1-32862 detects alpha 2c Adrenoceptor from human samples. PA1-32862 has been successfully used in immunohistochemistry (paraffin tissue) applications. The PA1-32862 immunogen is: Synthetic peptide, KLH conjugated.Alpha-2-adrenergic receptors are members of the G protein-coupled receptor superfamily. They include 3 highly homologous subtypes: alpha2A, alpha2B, and alpha2C. These receptors have a critical role in regulating neurotransmitter release from sympathetic nerves and from adrenergic neurons in the central nervous system. The mouse studies revealed that both the alpha2A and alpha2C subtypes were required for normal presynaptic control of transmitter release from sympathetic nerves in the heart and from central noradrenergic neurons. The alpha2A subtype inhibited transmitter release at high stimulation frequencies, whereas the alpha2C subtype modulated neurotransmission at lower levels of nerve activity. This gene encodes the alpha2C subtype, which contains no introns in either its coding or untranslated sequences.
|alpha-2c Adrenergic Receptor
|Synthetic peptide, KLH conjugated.
|ADRA2L2, ADRA2RL2, ADRARL2, ALPHA2CAR
|Antigen affinity chromatography
|Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
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