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MilliporeSigma™ anti-alpha-Actin Clone: 1A4,

Mouse Monoclonal Antibody

Manufacturer:  MilliporeSigma™ 113200500UL

Catalog No. 11-320-0500UL

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Specifically detects α-Actin Clone: 1A4 in Baboon, Human, Rabbit samples, and it is validated for Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin)

Actin is a cytoskeletal protein. Smooth muscle actin forms smaller, less ordered contractile units than actin from skeletal or cardiac muscle. The activity and state of assembly of smooth muscle actin is controlled by calcium-regulated phosphorylation of one of the myosin light chains.


In 150mM NaCl, 20mM Tris-borate, BHC-6 carrier polysaccharides, pH 7.5.
Recognizes α-actin in smooth muscle cells of blood vessels and parenchymal tissue of the intestine, testis, and ovary. Does not recognize actin from fibroblasts (β- and γ-cytoplasmic), striated muscle (α-sarcomeric), or myocardium (α-myocardial). Antibody Target Gene Symbol: ACTA2 Target Synonym: 0610041G09RIK, a-SMA, AAT6, ACTSA, Actvs, ALPHA ACTIN VSM, ALPHA SMA, ALPHA SMOOTH MUSCLE ACTIN, ALPHA-ACTIN 2, FLJ45296, MGC127800, RGD: 621676, Similar to vascular alpha actin, Sm alpha actin, SMalphaA, SMOOTH MUSCLE ALPHA ACTIN Entrez Gene Name: actin, alpha 2, smooth muscle, aorta
Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin)
a synthetic peptide corresponding to amino acids 1-10 of human smooth muscle α-actin.
2°C to 8°C
Baboon, Human, Rabbit
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