alpha B Crystallin Polyclonal Antibody, Invitrogen™

alpha B Crystallin Antibody, PA1-16950, from Invitrogen™. Species Reactivity: Human, Mouse; Applications: Immunocytochemistry, Immunofluorescence, Western Blot.

Manufacturer: Invitrogen PA116950

Catalog No. 01-950-179

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    Specifications

    Antigen alpha B Crystallin
    Applications Immunocytochemistry,Immunofluorescence,Western Blot
    Conjugate Unlabeled
    Cross Reactivity Human,Mouse
    Format Purified
    Formulation 100μL purified antibody (1.08mg/mL) in tris citrate and 0.1% sodium azide; pH 7-8
    Gene Accession No. P02511, P23927
    Gene Alias Alpha crystallin B chain antibody, CryAB antibody, Alpha (B)-crystallin antibody, Rosenthal fiber componet antibody, Heat-shock protein beta-5 antibod
    Gene Symbols CRYAB
    Host Species Rabbit
    Immunogen Synthetic peptide between amino acids 70-140 of the human Crystallin AB protein.
    Isotype IgG
    Quantity 100μL
    Species Reactivity Human, Mouse
    Storage Requirements Store at 4° C
    Primary or Secondary Primary
    Monoclonal or Polyclonal Polyclonal
    Gene ID (Entrez) 12955, 1410

    alpha B Crystallin Antibody, PA1-16950, from Invitrogen. Species Reactivity: Human, Mouse; Applications: Immunocytochemistry, Immunofluorescence, Western Blot.

    Crystallin AB (CryAB) is a developmentally regulated small heat shock protein known to protect cells from stress damage. It may also play an important role in the Golgi reorganization during cell division. CryAB is known to be associated with a number of neurodegenerative pathologies such as Alzheimer disease amd multiple sclerosis. As well, it has been found to be expressed in breast tumors of patients with shorter survival, suggesting that it may be a useful marker in identifying aggressive breast cancer.
    Host Species: Rabbit
    Cross Reactivity: Human, Mouse
    Isotype: IgG
    Immunogen: Synthetic peptide between amino acids 70-140 of the human Crystallin AB protein.
    Formulation: 100µL purified antibody (1.08mg/mL) in tris citrate and 0.1% sodium azide; pH 7-8
    Synonyms: Alpha crystallin B chain antibody, CryAB antibody, Alpha (B)-crystallin antibody, Rosenthal fiber componet antibody, Heat-shock protein beta-5 antibod
    Uniprot Accession: P02511, P23927
    Entrez GeneID: 12955, 1410
    Gene Symbol: CRYAB
    This Crystallin AB antibody is useful for Western blot analysis, where a band is seen at ~20 kDa. There is also a band of greater intensity at ~40 kDa that may be an aggregated heteromeric complex. CryAB aggregates with homologous proteins, including CryAA and the small heat shock protein HSP28, to form large heteromeric complexes.Suggested positive control: human and mouse skeletal muscle lysate, human skeletal muscle protein, antigen standard for HSPB1 (transient overexpression lysate), mouse skeletal muscle protein.

  • Description & Specifications

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