Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More

CRYAB Rabbit anti-Bovine, Hamster, Human, Mouse, Porcine, Rabbit, Rat, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA120795

Catalog No. PA120795

Add to cart



PA1-20795 detects AlphaB Crystallin in Human, Mouse, Rat, Bovine and Porcine samples. Expected to cross react with hamster and rabbit due to sequence homology. This antibody will not cross react with beta Crystallin nor alpha A Crystallin. PA1-20795 has been successfully used in Immunocytochemistry, Immunoprecipitation and Western Blot procedures. Detects a band ~22 kDa. PA1-20795 immunogen corresponds to synthetic peptide:R(163)EEKPAVTAAPKK(175) KLH conjugated, corresponding to human alpha B Crystallin. Store product as a concentrated solution. Centrifuge briefly prior to opening the vial. For short-term storage (1-2 weeks), product can be stored at 4°C. For long-term storage, aliquot and store product at -20° C or below, avioiding multiple freeze-thaw cycles.

Lens proteins consist almost entirely of Crystallins (about 95%). Crystallins are also found in vertebrate skeletal muscle tissue. In the lens, their structural function is to assist in maintaining the proper refractive index of the lens. The mammalian lens contains 3 major classes of crystallins: alpha, beta, and gamma. Alpha Crystallin is the largest of the crystallins and is composed of 2 primary gene products; alpha A and alpha B. There are at least 5 different proteins comprising the beta Crystallins. The gamma Crystallins are monomeric, but there are at least 5 gamma Crystallins identified in bovine and rat lens. Alpha Crystallin comprises 40% of total lens protein composition. In addition to maintaining proper refractive index, it also functions in a chaperone like manner by preventing the formation of aggregates possibly leading to cataract formation. It is believed that the phosphorylated states of the alpha Crystallin occur in response to cellular stress and may serve a structural control function and play a role in protein maintece. Alpha B Crystallin has been linked to Alexander ft.s disease where it accumulates in brain cells of those afflicted.


Synthetic peptide:R(163)EEKPAVTAAPKK(175) KLH conjugated, corresponding to human alpha B Crystallin.
Protein A
Bovine, Hamster, Human, Mouse, Porcine, Rabbit, Rat
Immunocytochemistry, Immunofluorescence, Immunohistochemistry, Immunoprecipitation, Western Blot
1 mg/mL
PBS with 50% glycerol and 0.09% sodium azide
P02510, P02511, P23927, Q7M2W6, P41316, P23928
100 μL
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
100009295, 100519789, 100772623, 12955, 1410, 25420, 281719
Provide Content Correction

We continue to work to improve your shopping experience and your feedback regarding this content is very important to us. Please use the form below to provide feedback related to the content on this product.

Product Title

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.

Cancel Submit