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AFP Goat anti-Human, Polyclonal, Invitrogen™

Goat Polyclonal Antibody

Manufacturer:  Invitrogen PA135997

Catalog No. 01-672-200


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Description

Description

Reconstitute with 1 mL of distilled water.

AFP (Alpha Fetoprotein) is a major plasma protein produced by the yolk sac, intestinal tract and the liver during fetal life. AFP expression in adults is often associated with hepatoma or teratoma. However, hereditary persistence of AFP may also be found in individuals with no obvious pathology. The protein is thought to be the fetal counterpart of serum albumin, and AFP and albumin genes are present in tandem in the same transcriptional orientation on chromosome 4. AFP is found in monomeric, dimeric, and trimeric forms. AFP can also bind to copper ions, nickel ions, fatty acids and bilirubin. The level of AFP in amniotic fluid is used to measure renal loss of protein to screen for spina bifida and anencephaly. High level of serum AFP has been identified in patients with hepatocellular carcinomas (HCC), teratoblastoma, colorectal cancer, pancreatic cancer, and germ cell neoplasms.
Specifications

Specifications

AFP
Polyclonal
Unconjugated
AFP
Lyophilized
AFP
Human alpha-Fetoprotein.
Affinity chromatography
RUO
Antibody
Polyclonal
Human
ELISA, Immunohistochemistry
1 mg/mL
PBS with 50% glycerol and no preservative; pH 7.5
P02771
AFP
Goat
IgG
1 mg
4° C
Primary
174
Documents
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