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ALS2CR2 Rabbit anti-Bovine, Canine, Equine, Human, Mouse, Non-human primate, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA523276

Catalog No. PIPA523276


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Description

Description

ALS2CR2, a novel anti-apoptotic protein, belongs to the serine/threonine protein kinase STE20 subfamily. Due to the presence of a protein kinase domain with one of the active site residues altered, ALS2CR2 is known as pseudokinase. ALS2CR2 is a component of a complex involved in the activation of a master kinase serine/threonine kinase 11,  that regulates cell polarity and energy-generating metabolism and is known to regulate the relocation of this kinase from the nucleus to the cytoplasm. It is essential for G1 cell cycle arrest mediated by this kinase. ALS2CR2 is known to interact with the X chromosome-linked inhibitor of apoptosis protein, and thus enhances the anti-apoptotic activity of this protein via the JNK1 signal transduction pathway.
Specifications

Specifications

Als2Cr2
Polyclonal
Unconjugated
STRADB
Liquid
STRADB
Synthetic peptide (211 KHGQRHRAVYDFPQFSTS 228) of Als2Cr2 protein.
Protein A
RUO
Antibody
Polyclonal
Bovine, Canine, Equine, Human, Mouse, Non-human primate
Immunohistochemistry (Paraffin), Western Blot
0.5 mg/mL
PBS with 0.05% BSA and 0.05% sodium azide
Q9C0K7, Q8K4T3
PRO1038, ALS2CR2, CALS-21, ILPIP, ILPIPA, PAPK, ILP-interacting protein ILPIPA, STE20-related kinase adapter protein beta, STRAD beta, amyotrophic lateral sclerosis 2 (juvenile) chromosome region, candidate 2, amyotrophic lateral sclerosis 2 chromosomal region candidate gene 2 protein, pseudokinase ALS2CR2
Rabbit
IgG
100 μg
-20° C, Avoid Freeze/Thaw Cycles
Primary
100066574, 227154, 478870, 506029, 55437
Documents
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