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Amylin Rabbit anti-Feline, Guinea Pig, Human, Porcine, Rat, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA136038

Catalog No. 01-672-227


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Description

Description

Suggested positive controls for IHC include human and rat pancreas. Recommended dilutions are 1:800-1:1500 using PAP, or 1:300-1:500 using FITC with over-night incubation at 4°C. Reconstitute with 50-100 µL of distilled water, and dilute further in 0.1M PBS with 1% BSA and 0.1% sodium azide. For long-term storage, aliquot and store at -20°C.

Islet, or insulinoma, amyloid polypeptide is commonly found in pancreatic islets of patients suffering diabetes mellitus type II, or harboring an insulinoma. While the assosciation of amylin with the development of type II diabetes has been known for some time, a direct causative role for amylin has been harder to establish. Studies suggest that amylin, like the related beta-amyloid (Abeta) associated with Alzheimer ft.s disease, can induce apoptotic cell-death in particular cultured cells, an effect that may be relevant to the development of type II diabetes.
Specifications

Specifications

Amylin
Polyclonal
whole serum with no preservative
P12967, P12966, P10997, Q29119, P12969
Rabbit Anti-Amylin
Rabbit
IgG
RUO
Antibody
Polyclonal
Feline, Guinea Pig, Human, Porcine, Rat
Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin)
Unconjugated
IAPP
Lyophilized
IAPP
Amylin.
50 μL
4° C
Primary
100135550, 100520838, 24476, 3375, 751513
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