anti-Amyloid beta A4 Polyclonal, Thermo Scientific™

Amyloid beta A4 Polyclonal antibody PA1-18317 from Thermo Scientific™ specifically detects Amyloid beta A4 in Rat samples, and it is validated for Immunohistochemistry

Manufacturer: Thermo Scientific PA118317

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Catalog No. 01-670-570

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    Specifications

    Antigen Amyloid beta A4
    Applications Immunohistochemistry
    Conjugate Unlabeled
    Cross Reactivity Rat
    Format Serum
    Formulation 100μL unpurified Antibody in whole serum, with no preservative;
    Gene Accession No. P08592
    Gene Alias APP, ABPP, Alzheimer disease amyloid protein, Cerebral vascular amyloid peptide, CVAP; Protease nexin-II, PN-II, APPI, PreA4, A4, AD1
    Gene Symbols App
    Host Species Rabbit
    Immunogen C-H(388) A H F Q K A K E R L E A K H R E R(405)
    Isotype IgG
    Quantity 100μL
    Species Reactivity Rat
    Storage Requirements Avoid Freeze/Thaw Cycles
    Primary or Secondary Primary
    Monoclonal or Polyclonal Polyclonal
    Gene ID (Entrez) 54226

    Amyloid beta A4 Polyclonal antibody PA1-18317 from Thermo Scientific™ specifically detects Amyloid beta A4 in Rat samples, and it is validated for Immunohistochemistry

    APP functions as a cell surface receptor and performs physiological functions on the surface of neurons relevant to neurite growth, neuronal adhesion and axonogenesis. The APP protein is involved in cell mobility and transcription regulation through protein-protein interactions. APP can promote transcription activation through binding to APBB1/Tip60 and inhibit Notch signaling through interaction with Numb. APP couples to apoptosis-inducing pathways such as those mediated by G(O) and JIP. Inhibits G(o) alpha ATPase activity. Acts as a kinesin I membrane receptor, mediating the axonal transport of beta-secretase and presenilin 1.
    Host Species: Rabbit
    Cross Reactivity: Rat
    Isotype: IgG
    Immunogen: Synthetic peptides corresponding to residuess C-E(145) T H L H W H T V A K E T(157), C-H(388) A H F Q K A K E R L E A K H R E R(405), and C-K(724) K K
    Formulation: 100µL Unpurified Antibody in whole serum, with no preservative
    Synonyms: APP, ABPP, Alzheimer disease amyloid protein, Cerebral vascular amyloid peptide, CVAP; Protease nexin-II, PN-II, APPI, PreA4, A4, AD1
    Uniprot Accession: P08592
    Entrez GeneID: 54226
    Gene Symbol: App
    PA1-18317 detects APP from rat samples. PA1-18317 has been successfully used in immunohistochemistry procedures. The PA1-18317 immunogen is a synthetic peptides corresponding to residuess C-E(145) T H L H W H T V A K E T(157), C-H(388) A H F Q K A K E R L E A K H R E R(405), and C-K(724) K K Q Y T S I H H G V V E(737) of human APP isoform A, conjugated to KLH. Reconstitute with 100 ul of distilled water.

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