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Amyloid Precursor Protein Rabbit anti-Rat, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA14648

Catalog No. PA14648


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Description

Description

This antibody is predicted to react with canine, chicken, human, mouse and non-human primate based on 100% sequence homology. This antibody is specific for ~115 kDa APP protein. Immunolabeling of the APP protein band is completely blocked by preadsorption of the antibody with the peptide used as antigen.

Amyloid Precursor Protein (APP) or Amyloid beta protein functions as a cell surface kinesin I membrane receptor, mediating the axonal transport of beta-secretase and presenilin 1; APP is rapidly internalized via clathrin-coated pits. APP is important for neurite growth, neuronal adhesion and axonogenesis. Mutations in the APP gene can lead to Alzheimer disease 1 (AD1). This anitbody recognizes APP (b-APP770) with a MW of approximately 100kDa.
Specifications

Specifications

Amyloid Precursor Protein
Polyclonal
0.01M HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and no preservative; pH 7.5
P08592
APP, AAA antibody, Amyloid beta A4 protein, ABPP, Alzheimer disease amyloid protein, Cerebral vascular amyloid peptide, CVAP, Protease nexin-II, PN-II
Rabbit
IgG
100 μL
-20° C, Avoid Freeze/Thaw Cycles
Primary
54226
Western Blot
Unconjugated
App
Liquid
APP
Synthetic peptide corresponding to the C-terminal region of rat APP conjugated to KLH
Affinity chromatography
RUO
Antibody
Polyclonal
Rat
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