Amyloid Precursor Protein Rabbit anti-Human, Mouse, Rat, Polyclonal, Invitrogen
Rabbit Polyclonal Antibody
Manufacturer: Invitrogen PA112527
This antibody is predicted to react with rabbit, pig, bovine, guinea pig and chicken based on sequence homology. In Western blot, this antibody detects a ~120 kDa band in human, mouse and rat brain tissue lysates.Amyloid Precursor Protein (APP) or Amyloid beta protein functions as a cell surface kinesin I membrane receptor, mediating the axonal transport of beta-secretase and presenilin 1; APP is rapidly internalized via clathrin-coated pits. APP is important for neurite growth, neuronal adhesion and axonogenesis. Mutations in the APP gene can lead to Alzheimer disease 1 (AD1). This anitbody recognizes APP (b-APP770) with a MW of approximately 100kDa.
|Amyloid Precursor Protein|
|Synthetic peptide corresponding to residues 653-662 of human amyloid A4 protein precursor.|
|Antigen affinity chromatography|
|Human, Mouse, Rat|
|PBS with 0.02% sodium azide|
|P05067, P12023, P08592|
|Amyloid beta A4 protein, ABPP, Alzheimer disease amyloid protein, Cerebral vascular amyloid peptide, CVAP; Protease nexin-II, PN-II, APPI, PreA4, A4,|
|-20° C, Avoid Freeze/Thaw Cycles|
|11820, 351, 54226|
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