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Amyloid Precursor Protein Rabbit anti-Human, Mouse, Rat, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA112527

Catalog No. 01-674-187


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Description

Description

This antibody is predicted to react with rabbit, pig, bovine, guinea pig and chicken based on sequence homology. In Western blot, this antibody detects a ~120 kDa band in human, mouse and rat brain tissue lysates.

Amyloid Precursor Protein (APP) or Amyloid beta protein functions as a cell surface kinesin I membrane receptor, mediating the axonal transport of beta-secretase and presenilin 1; APP is rapidly internalized via clathrin-coated pits. APP is important for neurite growth, neuronal adhesion and axonogenesis. Mutations in the APP gene can lead to Alzheimer disease 1 (AD1). This anitbody recognizes APP (b-APP770) with a MW of approximately 100kDa.
Specifications

Specifications

Amyloid Precursor Protein
Polyclonal
Unconjugated
APP
Liquid
APP
Synthetic peptide corresponding to residues 653-662 of human amyloid A4 protein precursor.
Antigen affinity chromatography
RUO
Antibody
Polyclonal
Human, Mouse, Rat
Western Blot
0.5 mg/mL
PBS with 0.02% sodium azide
P05067, P12023, P08592
Amyloid beta A4 protein, ABPP, Alzheimer disease amyloid protein, Cerebral vascular amyloid peptide, CVAP; Protease nexin-II, PN-II, APPI, PreA4, A4,
Rabbit
IgG
100 μg
-20° C, Avoid Freeze/Thaw Cycles
Primary
11820, 351, 54226
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