Angiopoietin 2 Goat anti-Human, Polyclonal, Invitrogen
Goat Polyclonal Antibody
Manufacturer: Invitrogen PA120178
PA1-20178 detects Angiopoietin 2 in human samples. PA1-20178 has been successfully used in ELISA and Western blot procedures. The PA1-20178 immunogen is recombit, full length, human Angiopoietin 2. Store product as a concentrated solution. Centrifuge briefly prior to opening the vial. For short-term storage (1-2 weeks), product can be stored at 4°C. For long-term storage, aliquot and store product at -20° C or below, avioiding multiple freeze-thaw cycles.Angiopoietin 2 and angiopoietin 1 have an N-terminal coiled-coil domain and a C-terminal fibrinogen-like domain. The coiled coil domains mediate ligand homo-oligomerization and the fibrinogen-like domains mediate ligand activity. Recombit human angiopoietin 2 has a molecular mass of approximately 66 kDa in SDS-PAGE under reducing and non-reducing conditions. Angiopoietin 2 probably acts as a natural antagonist for Ang1 and Tie2 both in vivo and in vitro. In adult mice and humans, angiopoietin 2 is expressed at sites of vascular remodeling.
|Recombit, full length, human Angiopoietin 2.|
|Antigen affinity chromatography|
|ELISA, Western Blot|
|PBS with 5% trehalose and no preservative; pH 7.4|
|Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
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