Angiostatin Rabbit anti-Human, Mouse, Polyclonal, Invitrogen
Rabbit Polyclonal Antibody
Manufacturer: Invitrogen PA1600
PA1-600 detects recombit human and mouse angiostatin. PA1-600 has been successfully used in Western blot and ICC/IF procedures. By Western blot, this antibody detects a 50 kDa protein representing recombit human angiostatin. PA1-600 immunizing peptide corresponds to amino acid residues 98-116 from mouse angiostatin. This sequence is 95% and 84% conserved in rat and human angiostatin, respectively. PA1-600 can be used with blocking peptide PEP-111.Angiostatin is a proteolytic fragment that comprises the first four kringle domains of the ~85 kDa plasminogen. Angiostatin reduces endothelial cell proliferation and acts as an potent inhibitor of angiogenesis and tumor growth.
|Synthetic Peptide: V(98) Y L S E C K T G I G N G Y R G T M S(116)|
|Antigen affinity chromatography|
|Immunocytochemistry, Immunofluorescence, Western Blot|
|PBS with 1mg/mL BSA and 0.05% sodium azide|
|Plasminogen, Microplasmin, PLG|
|-20° C, Avoid Freeze/Thaw Cycles|
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