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Angiotensin I Rabbit anti-Human, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA136039

Catalog No. 01-672-228


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Description

Description

The protein encoded by this gene, pre-angiotensinogen or angiotensinogen precursor, is expressed in the liver and is cleaved by the enzyme renin in response to lowered blood pressure. The resulting product, angiotensin I, is then cleaved by angiotensin converting enzyme (ACE) to generate the physiologically active enzyme angiotensin II. The protein is involved in maintaining blood pressure and in the pathogenesis of essential hypertension and preeclampsia. Mutations in this gene are associated with susceptibility to essential hypertension, and can cause renal tubular dysgenesis, a severe disorder of renal tubular development. Defects in this gene have also been associated with non-familial structural atrial fibrillation, and inflammatory bowel disease.

Reconstitute with 1 ml of distilled water and add preservative if preferred.
Specifications

Specifications

Angiotensin I
Polyclonal
whole serum with no preservative
P01019
RABBIT anti Human ANGIOTENSIN I
Rabbit
IgG
RUO
Antibody
Polyclonal
Human
ELISA
Unconjugated
AGT
Lyophilized
AGT
Polyclonal Rabbit anti Angiotensin I antibody.
1 mL
4° C
Primary
183
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