Annexin I Mouse, Unlabeled, Clone: 29, BD
Mouse Monoclonal Antibody
Manufacturer: BD Biosciences 610066
Annexin I, also known as lipocortin-1 or calpactin II, is part of a calcium-dependent phospholipid-binding protein family. Members share a common core domain, but each has a unique N-terminal tail that imparts its functional specificity. It is believed that phosphorlyation of this region in annexin I regulates its functions. Annexin I has been implicated in regulating phospholipid vesicle aggregation, mediating inflammatory response, and inhibiting the activity of phospholipase A2. Additionally, it has been found that the 10kDa protein S100C influences annexin I's activity by binding to the N-terminal 13 residues of annexin in a manner similar to that of the annexin II/p11 complex.
Host Species: Mouse
Species Reactivity: Human
Immunogen: Cow Annexin I aa. 1-346
Formula Weight [Chemical]: 38kDa
Immunofluorescence, Immunohistochemistry, Immunoprecipitation, Western Blotting
|Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.|
|Store undiluted at -20°C.|
|Lipocortin-1; Calpactin II|
|Cow Annexin I aa. 1-346|
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