Annexin A6 Rabbit anti-Human, Polyclonal, Invitrogen™
Rabbit Polyclonal Antibody
Manufacturer: Invitrogen PA137086
This antibody is predicted to react with bovine, canine, mouse, porcine based on sequence homology. Heat-mediated antigen retrieval is recommended prior to staining, using a 10mM citrate buffer, pH 6.0, for 10 minutes followed by cooling at room temperature for 20 min. Following antigen retrieval, incubate samples with primary antibody for 30 min at room temperature. A suggested positive control is liver tissue.The Annexin family of calcium-binding proteins is composed of al least ten mammalian genes. It is characterized by a conserved core domain which binds to phospholipids in a Ca2+-dependent manner and a unique amino terminal region which may confer binding specificity. The Annexin family has been implicated as regulators of such diverse processes as ion-flux, endocytosis and exocytosis, and cellular adhesion. When overexpressed in A431 cells, Annexin VI causes a partial reversal of the transformed phenotype.
|PBS with 1% BSA and <0.1% sodium azide; pH 7.4|
|ANX6, CBP68, 67 kDa calelectrin, CPB-II, annexin VI p68, annexin-6, calcium-binding protein p68, calelectrin, calphobindin II, calphobindin-II, chromobindin-20, lipocortin VI, p68, p70|
|Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
|Immunohistochemistry (Paraffin), Western Blot|
|Synthetic peptide corresponding to N-terminus of human Annexin VI.|
|Antigen affinity chromatography|
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