Annexin A6 Rabbit anti-Human, Mouse, Polyclonal, Invitrogen
Rabbit Polyclonal Antibody
Manufacturer: Invitrogen PA527462
PA5-27462 targets Annexin VI in IHC (P) and WB applications and shows reactivity with Human and mouse samples. The PA5-27462 immunogen is recombit fragment corresponding to a region within amino acids 475 and 673 of Human Annexin VI. Store product as a concentrated solution. Centrifuge briefly prior to opening the vial. For short-term storage (1-2 weeks), product can be stored at 4°C. For long-term storage, aliquot and store product at -20° C or below, avioiding multiple freeze-thaw cycles.Annexin VI belongs to a family of calcium-dependent membrane and phospholipid binding proteins. Although their functions are still not clearly defined, several members of the annexin family have been implicated in membrane-related events along exocytotic and endocytotic pathways. The annexin VI gene is approximately 60 kbp long and contains 26 exons. It encodes a protein of about 68 kDa that consists of eight 68-amino acid repeats separated by linking sequences of variable lengths. It is highly similar to human annexins I and II sequences, each of which contain four such repeats. Exon 21 of annexin VI is alternatively spliced, giving rise to two isoforms that differ by a 6-amino acid insertion at the start of the seventh repeat. Annexin VI has been implicated in mediating the endosome aggregation and vesicle fusion in secreting epithelia during exocytosis.
|Recombit fragment corresponding to a region within amino acids 475 and 673 of Human Annexin VI|
|Antigen affinity chromatography|
|Immunohistochemistry (Paraffin), Western Blot|
|PBS with 10% glycerol and 0.01% thimerosal; pH 7|
|ANX6, CBP68, 67 kDa calelectrin, CPB-II, annexin VI (p68), annexin-6, calcium-binding protein p68, calelectrin, calphobindin II, calphobindin-II, chromobindin-20, lipocortin VI, p68, p70|
|Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
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