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Annexin A6 Rabbit anti-Human, Mouse, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA527462

Catalog No. PIPA527462


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Description

Description

PA5-27462 targets Annexin VI in IHC (P) and WB applications and shows reactivity with Human and mouse samples. The PA5-27462 immunogen is recombit fragment corresponding to a region within amino acids 475 and 673 of Human Annexin VI. Store product as a concentrated solution. Centrifuge briefly prior to opening the vial. For short-term storage (1-2 weeks), product can be stored at 4°C. For long-term storage, aliquot and store product at -20° C or below, avioiding multiple freeze-thaw cycles.

Annexin VI belongs to a family of calcium-dependent membrane and phospholipid binding proteins. Although their functions are still not clearly defined, several members of the annexin family have been implicated in membrane-related events along exocytotic and endocytotic pathways. The annexin VI gene is approximately 60 kbp long and contains 26 exons. It encodes a protein of about 68 kDa that consists of eight 68-amino acid repeats separated by linking sequences of variable lengths. It is highly similar to human annexins I and II sequences, each of which contain four such repeats. Exon 21 of annexin VI is alternatively spliced, giving rise to two isoforms that differ by a 6-amino acid insertion at the start of the seventh repeat. Annexin VI has been implicated in mediating the endosome aggregation and vesicle fusion in secreting epithelia during exocytosis.
Specifications

Specifications

Annexin A6
Polyclonal
Unconjugated
ANXA6
Liquid
ANXA6
Recombit fragment corresponding to a region within amino acids 475 and 673 of Human Annexin VI
Antigen affinity chromatography
RUO
Antibody
Polyclonal
Human, Mouse
Immunohistochemistry (Paraffin), Western Blot
0.179 mg/mL
PBS with 10% glycerol and 0.01% thimerosal; pH 7
P08133, P14824
ANX6, CBP68, 67 kDa calelectrin, CPB-II, annexin VI (p68), annexin-6, calcium-binding protein p68, calelectrin, calphobindin II, calphobindin-II, chromobindin-20, lipocortin VI, p68, p70
Rabbit
IgG
100 μL
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Primary
11749, 309
Documents
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